Data synthesis: Network Meta Analysis (NMA)
Head to head trials involving two or more interventions are expensive and time consuming. As such, they primarily serve a regulatory purpose and, where appropriate, are limited to placebo-controlled trials.
However, the ‘which intervention is better?’ question remains.
The NMA is a better approach to use data in the public domain to model expected outcomes from two or more interventions. Recognised by NICE as
a valid approach to understand these expected outcomes in the absence of head to head data, Medialis has vast experience in designing and executing these for publication in support of medical objectives.