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Vaccines US Expert Consensus

Reference: Chatterjee A, Ambrose K, Canaday DH, Delair S, Ezike N, Huber VC, Jhaveri R, Nyquist AC, Sporer A, Varman M, Vivekanandan R. The association between influenza vaccine effectiveness and egg-based manufacturing technology: literature review and US expert consensus. Current medical research and opinion. 2024 Feb 1;40(2):335-43. Background Influenza is associated with significant disease burden...

nAMD Costs (1)

Reference: Sivaprasad S, Bailey C, Downey L, Gilbert R, Gale R, Kotagiri A, Mahmood S, Morgan-Warren P, Napier J, Narendran N, Pearce I. . Real-world service costs for neovascular-AMD clinics in the United Kingdom: structured literature review and scenario analysis. Current Medical Research and Opinion. 2024 Jul 2;40(7):1221-33. Objective Current cost-effectiveness analyses (CEA) emphasize drug...

Acute pancreatitis core dataset

Reference: Freedman S, De-Madaria E, Singh VK, Bruckert E, Löhr M, Sutton R, Rebours V, Jones R, Jandhyala R. A simple core dataset for triglyceride-induced acute pancreatitis. Current Medical Research and Opinion. 2023 Jan 2;39(1):37-46.   Objective  The objective of this study is to generate a core clinical dataset (CD) containing the minimum acceptable amount of...

MAPP value to pharmaceutical industry

Reference: Jandhyala R, Rout R. Observing expert opinion of medical affairs pharmaceutical physicians on the value of their clinical experience to the pharmaceutical industry using the Jandhyala method. Current Medical Research and Opinion. 2023 Dec 2;39(12):1541-50.   Background  The pharmaceutical industry requires a highly qualified workforce with diverse skillsets. Medical affairs pharmaceutical physicians (MAPPs) have unique...

jandhyala method

We @Medialis Ltd are pleased to share with you the second of a series of updates on the #medicalaffairs principles underlying our work, the four pillars of our medical #thirty22RWEstrategy in the #pharmaceuticalindustry, #rarediseases and #orphandrugs. Pillar 2 of our strategy focuses on the application of #Neutraltheory via the #Jandhyalamethod to observe #consensusopinion from #keyopinionleaders...

Medialis Ltd is thrilled to announce the completion of our first proprietary software application: JeMa (Jandhyala Method Application). This app enables us to seamlessly administer the #JandhyalaMethod, shortening the time to delivery of the completed research for our clients considerably. Incorporating our own state-of-the-art AI, JeMa will enable Medialis to further develop our algorithms to...

vaccines

This work, carried out by Medialis, is the first study to estimate the impact of egg-adaptations on #influenzavaccine effectiveness. Our experts agreed that compared to TIVs and QIVs, avoiding egg-adaptations could improve #influenza #vaccineeffectiveness by up to 16%, suggesting that new technologies that avoid egg-based manufacture could deliver increased benefit to patients. We used the...

FGF23 and its role in X-linked hypophosphatemia-related morbidity

Background X-linked hypophosphatemia (XLH) is an inherited disease of phosphate metabolism in which inactivating mutations of the Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) gene lead to local and systemic effects including impaired growth, rickets, osteomalacia, bone abnormalities, bone pain, spontaneous dental abscesses, hearing difficulties, enthesopathy, osteoarthritis, and muscular dysfunction. Patients with XLH present with elevated levels of...

mapp

Background A pilot study conducted in 2020 suggested that Medical Affairs Pharmaceutical Physicians (MAPPs) may be inherently undervalued within the pharmaceutical industry and vulnerable to replacement by less qualified roles. There are currently no standardized metrics to measure MAPP performance, thus it is necessary to measure the value of MAPPs to employers and clarify the...